Rüffer M, Steipe B, Zenk M H
Lehrstuhl für Pharmazeutische Biologie, Ludwig-Maximilians-Universität München, Germany.
FEBS Lett. 1995 Dec 18;377(2):175-80. doi: 10.1016/0014-5793(95)01334-2.
It was demonstrated that salicylic acid (SA) not only binds to catalase from differentiated higher plants and plant cell suspension cultures but also to those of fungi and animals. SA bound specifically to iron-containing enzymes, such as catalase, aconitase, lipoxidase and peroxidase, while not to iron-free plant enzymes. On the grounds of these experiments, the claim is further challenged that SA is a signalling compound and second messenger in plants that activates plant defense-related genes through elevated H2O2 levels by specifically inhibiting catalase activity. SA may just function as a phytoalexin.
已证明水杨酸（SA）不仅能与分化的高等植物和植物细胞悬浮培养物中的过氧化氢酶结合，还能与真菌和动物的过氧化氢酶结合。SA特异性地与含铁酶结合，如过氧化氢酶、乌头酸酶、脂氧化酶和过氧化物酶，而不与不含铁的植物酶结合。基于这些实验，SA作为一种信号化合物和植物中的第二信使，通过特异性抑制过氧化氢酶活性，提高H2O2水平来激活植物防御相关基因这一说法受到了进一步质疑。SA可能仅起到植物抗毒素的作用。
