Tanihara H, Negi A, Akimoto M, Nagata M
Department of Ophthalmology, Tenri Hospital, Nara, Japan.
Graefes Arch Clin Exp Ophthalmol. 1995 Sep;233(9):563-7. doi: 10.1007/BF00404707.
We previously reported the effectiveness of goniosynechialysis and trabeculotomy ab externo for adult-onset glaucoma. In this study, we performed non-filtering surgery on patients with primary angle-closure glaucoma and studied the long-term outcome of this treatment.
Included in this study were 35 eyes of 25 patients with primary angle-closure glaucoma, each of which had an intraocular pressure greater than 20 mmHg with maximal tolerated antiglaucoma medication, even after laser iridotomy or surgical iridectomy. Of these 35 eyes, 22 underwent trabeculotomy and 13 underwent goniosynechialysis. All patients were followed up for at least 18 months.
In 21 (95%) of 22 eyes after trabeculotomy, and in 12 (92%) of 13 eyes after goniosynechialysis, intraocular pressures were well controlled at or below 21 mmHg at the final examination. However, in two of the 21 eyes in which trabeculotomy was a success, and in four of the 12 eyes in which goniosynechialysis was successful, the procedure had to be repeated before adequate control of pressure was achieved.
Our results show that intraocular pressure in most cases of primary angle-closure glaucoma can be controlled by restructuring of the physiologic aqueous outflow route by means of goniosynechialysis or trabeculotomy, and that filtering surgery is not necessary.
我们之前报道了房角切开术和外路小梁切开术治疗成人开角型青光眼的有效性。在本研究中,我们对原发性闭角型青光眼患者进行了非滤过性手术,并研究了该治疗方法的长期疗效。
本研究纳入了25例原发性闭角型青光眼患者的35只眼,即使在激光虹膜切开术或手术虹膜切除术后,使用最大耐受量抗青光眼药物治疗时,这些眼睛的眼压仍高于20 mmHg。在这35只眼中,22只接受了小梁切开术,13只接受了房角切开术。所有患者均随访至少18个月。
小梁切开术后22只眼中的21只(95%),房角切开术后13只眼中的12只(92%),在末次检查时眼压得到良好控制,降至21 mmHg或更低。然而,在小梁切开术成功的21只眼中,有2只,在房角切开术成功的12只眼中,有4只,在眼压得到充分控制之前不得不重复手术。
我们的结果表明,大多数原发性闭角型青光眼病例的眼压可以通过房角切开术或小梁切开术重建生理性房水流出途径来控制,无需进行滤过性手术。