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[静脉输注葡萄糖负荷对急性脑血管病极早期患者血糖、果糖水平及血清葡萄糖-6-磷酸异构酶活性的影响]

[Effect of intravenous glucose load on blood glucose and fructose level and glucose-6-phosphate isomerase activity in serum of patients with acute cerebrovascular disease in its earliest phase].

作者信息

Szewczyk K M

机构信息

Katedry i Kliniki Neurologii Akademii Medycznej, Lublinie.

出版信息

Neurol Neurochir Pol. 1995 Jul-Aug;29(4):497-505.

PMID:8544928
Abstract

The purpose of the study was to investigate the dynamics of glucose and fructose concentrations in the blood changes and phosphohexose isomerase activity (PHI) in serum of unfed or after intravenous glucose injection patients, with acute cerebrovascular disease in the earliest period of illness. The investigation was done in 15 patients with transient ischaemic attacks, 30 patients with cerebral ischaemic stroke and 15 patients with cerebral haemorrhage. In patients with different forms of acute cerebrovascular damage it was found that there was hyperglycaemia in the blood of unfed patients, elevated blood fructose level and increased serum PHI activity; those changes were increased by intravenous glucose administration. The changes were most expressed in the group of patients with cerebral haemorrhage and cerebral ischaemic stroke.

摘要

该研究的目的是调查未进食或静脉注射葡萄糖后,处于疾病最早阶段的急性脑血管疾病患者血液中葡萄糖和果糖浓度的变化以及血清中磷酸己糖异构酶活性(PHI)。对15例短暂性脑缺血发作患者、30例脑缺血性中风患者和15例脑出血患者进行了调查。在不同形式急性脑血管损伤的患者中发现,未进食患者血液中存在高血糖,血中果糖水平升高且血清PHI活性增加;静脉注射葡萄糖后这些变化加剧。这些变化在脑出血和脑缺血性中风患者组中表现最为明显。

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