高血压大鼠对前列腺素的肺部灭活作用。

Pulmonary inactivation of prostaglandin by hypertensive rats.

作者信息

Leary W P, Asmal A C, Botha J

出版信息

Prostaglandins. 1977 Apr;13(4):697-700. doi: 10.1016/0090-6980(77)90241-6.

Abstract

Lungs of normotensive and genetically hypertensive (GH) albino rats were perfused in stiu with 5 ml/min Krebs solutuion containing 100 ng/ml PGE2 or F2alpha. Inactivation rates of 76,0 ng PGF2 alpha and 146,3 ng PGE2/g dry wt. lung/min were recorded for GH rats. Values for normotensive controls were 191,2 and 226,1 ng/g/min.

摘要

以每分钟5毫升含100纳克/毫升前列腺素E2（PGE2）或前列腺素F2α（F2alpha）的克雷布斯溶液对正常血压和遗传性高血压（GH）白化大鼠的肺进行原位灌注。记录到GH大鼠每克干重肺组织每分钟对76.0纳克前列腺素F2α和146.3纳克前列腺素E2的灭活率。正常血压对照组的值分别为191.2和226.1纳克/克/分钟。