Malkoff M D, Gomez C R, Myles G, Cruz-Flores S
Souers Stroke Institute, St. Louis, Missouri, USA.
Angiology. 1996 Jan;47(1):51-6. doi: 10.1177/000331979604700107.
Transcranial Doppler (TCD) measurements of middle cerebral artery (MCA) blood flow velocities were recorded and synchronized with electrocardiographic (EKG) recordings in 52 EKG/TCD complexes in 4 patients. Thirty-seven normal sinus beats and 13 conductive and 2 nonconductive premature ventricular contractions (PVCs) were examined. Mean velocities averaged 45 +/- 4 cm/sec for normal sinus rhythm (NSR) vs 26 +/- 4 cm/sec in the PVC group (P = 0.007). Peak systolic velocities averaged 74 +/- 6 cm/sec for the NSR and 45 +/- 7 cm/sec in the PVC group (P = 0.016). The latency between the QRS complexes and corresponding TCD wave forms (QRS-SU) averaged 0.12 +/- 0.03 sec in NSR AND 0.17 +/- 0.04 sec for the PVC group (P < 0.001). In addition, QRS-SU was inversely related to all velocities. PVCs appeared to be less hemodynamically efficient than NSR. The lower blood flow velocities and increased QRS-SU may result from lower stroke volume and delayed ventricular contraction associated with the aberrant QRS complex.
对4例患者的52份心电图/经颅多普勒（EKG/TCD）组合进行记录，测量大脑中动脉（MCA）血流速度并与心电图（EKG）记录同步。检查了37次正常窦性搏动、13次传导性和2次非传导性室性早搏（PVC）。正常窦性心律（NSR）的平均速度为45±4厘米/秒，而PVC组为26±4厘米/秒（P = 0.007）。NSR的收缩期峰值速度平均为74±6厘米/秒，PVC组为45±7厘米/秒（P = 0.016）。QRS复合波与相应TCD波形之间的延迟（QRS-SU）在NSR中平均为0.12±0.03秒，PVC组为0.17±0.04秒（P < 0.001）。此外，QRS-SU与所有速度呈负相关。PVC在血流动力学方面似乎不如NSR有效。较低的血流速度和增加的QRS-SU可能是由于与异常QRS复合波相关的较低搏出量和延迟的心室收缩所致。
