Fries J F, Singh G, Morfeld D, O'Driscoll P, Hubert H
Stanford University School of Medicine, California, USA.
Arthritis Rheum. 1996 Jan;39(1):64-72. doi: 10.1002/art.1780390109.
To determine, by longitudinal study, whether long-distance running, maintained for many years, is associated with increased musculoskeletal pain with age.
A 6-year prospective longitudinal study of 410 runners' club members and 289 community controls, age 53-75 years at study initiation, was conducted. Subjects were also categorized as ever-runners (n = 488) and never-runners (n = 211). The primary dependent variable was pain score as indicated on a horizontal double-anchored analog scale; data for this variable were available beginning in 1987. Statistical adjustment for age, education level, smoking, alcohol consumption, history of arthritis, and presence of other major medical conditions was done by analysis of covariance. Further analyses of previously reported associations of regular vigorous physical activity with decreased disability and mortality after 9 years were performed.
The degree of musculoskeletal pain was slightly lower in the exercise group compared with controls, and the difference was statistically significant for women but not for men. Average adjusted pain scores for men were 18.3 (SEM 0.8) in runners' club members, 20.2 (1.2) in controls, 18.6 (0.8) in ever-runners, and 20.3 (1.6) in never-runners. For women, these scores were 17.5 (1.8) in runners' club members versus 22.8 (1.4) in controls (P < 0.05), and 17.2 in ever runners versus 23.7 (1.5) in never-runners (P < 0.002). Disability had continued to develop in runners' club members at a rate only one-third that in the controls after 9 years of observation. Mortality over 9 years consisted of 51 deaths, of which 41 were in the control group and only 10 were among runners' club members.
Vigorous running activity over many years is not associated with an increase in musculoskeletal pain with age, and there may be a moderate decrease in pain, particularly in women. Vigorous physical activity is associated with greatly decreased levels of disability and with decreased mortality rates.
通过纵向研究确定多年坚持长跑是否会随着年龄增长而导致肌肉骨骼疼痛增加。
对410名跑步俱乐部成员和289名社区对照者进行了为期6年的前瞻性纵向研究，研究开始时年龄在53 - 75岁。受试者还被分为曾经跑步者（n = 488）和从未跑步者（n = 211）。主要因变量是水平双锚模拟量表所示的疼痛评分；该变量的数据从1987年开始可得。通过协方差分析对年龄、教育水平、吸烟、饮酒、关节炎病史和其他主要疾病状况进行统计调整。对先前报道的规律剧烈体育活动与9年后残疾和死亡率降低之间的关联进行了进一步分析。
与对照组相比，运动组的肌肉骨骼疼痛程度略低，女性的差异具有统计学意义，而男性则无。男性跑步俱乐部成员的平均调整后疼痛评分为18.3（标准误0.8），对照组为20.2（1.2），曾经跑步者为18.6（0.8），从未跑步者为20.3（1.6）。女性方面，跑步俱乐部成员的这些评分为17.5（1.8），对照组为22.8（1.4）（P < 0.05），曾经跑步者为17.2，从未跑步者为23.7（1.5）（P < 0.002）。经过9年观察，跑步俱乐部成员的残疾程度仍在发展，但其速度仅为对照组的三分之一。9年期间的死亡率为51例死亡，其中41例在对照组，仅10例在跑步俱乐部成员中。
多年的剧烈跑步活动与随着年龄增长肌肉骨骼疼痛增加无关，疼痛可能会适度减轻，尤其是在女性中。剧烈体育活动与残疾水平大幅降低和死亡率降低相关。
