Grafman J, Litvan I, Stark M
Cognitive Neuroscience Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA.
Brain Cogn. 1995 Aug;28(3):311-20. doi: 10.1006/brcg.1995.1260.
Progressive supranuclear palsy (PSP) is the epitome of a subcortical dementia process. Due to its relative rarity, there is only a small literature on the neuropsychological consequences of PSP. The findings to date demonstrate that PSP patients have dramatically slowed information processing and motor execution, rapid forgetting, problems in orienting attentional resources, and difficulty in planning and shifting conceptual sets. The pattern and severity of these deficits are unique to PSP and suggest that the study of PSP patients can provide a special insight into brain-behavior relations.
进行性核上性麻痹(PSP)是皮质下痴呆过程的典型代表。由于其相对罕见,关于PSP神经心理学后果的文献较少。迄今为止的研究结果表明,PSP患者的信息处理和运动执行显著减慢、快速遗忘、注意力资源定向存在问题以及规划和转换概念集存在困难。这些缺陷的模式和严重程度是PSP所特有的,表明对PSP患者的研究可以为脑-行为关系提供独特的见解。