Beaufrère B, Bresson J L, Briend A, Farriaux J P, Ghisolfi J, Navarro J, Rey J, Ricour C, Rieu D, Vidailhet M
Arch Pediatr. 1995 Dec;2(12):1209-18.
Infants, young children, and childbearing aged women are particularly exposed to iron deficiency. Pregnancy further increases iron requirements. Nevertheless the consequences of anemia and/or iron deficiency on pregnancy outcome, development of the foetus and postnatal iron status of the infant, remain to be determined. There is a 3-fold increase of premature deliveries in iron deficient anemic pregnant women whose anemia is discovered in early pregnancy: however this increased risk of premature delivery is not observed when iron deficiency anemia is discovered in late pregnancy. Iron supplementation during pregnancy improves the maternal hematological parameters but it is still unclear whether it also improves the maternal health and the pre and postnatal development of the child. Based on our actual knowledge, iron supplementation during pregnancy is to be recommended in risk groups only (ie mainly adolescents, low income women, women with multiple pregnancies), using ferrous iron at a dosage of 30 mg per day.
婴儿、幼儿和育龄妇女特别容易缺铁。怀孕会进一步增加铁的需求量。然而,贫血和/或缺铁对妊娠结局、胎儿发育以及婴儿出生后的铁状态的影响仍有待确定。在孕早期发现贫血的缺铁性贫血孕妇中,早产率增加了3倍:然而,在孕晚期发现缺铁性贫血时,并未观察到这种早产风险的增加。孕期补充铁剂可改善母体血液学参数,但目前尚不清楚它是否也能改善母体健康以及孩子的产前和产后发育。基于我们目前的认知,仅建议在高危人群(即主要是青少年、低收入女性、多胎妊娠女性)中孕期补充铁剂,使用剂量为每日30毫克的亚铁。