Nerlich A G, Parsche F, Wiest I, Schramel P, Löhrs U
Pathologisches Institut der Universität München, Germany.
Virchows Arch. 1995;427(4):423-9. doi: 10.1007/BF00199392.
We report on the morphological and trace element findings of several internal organs from an Egyptian mummy approximately dating from the year 950 B.C. according to 14C-analysis. By use of a multidisciplinary approach we succeeded in discovering evidence for severe and presumably recurrent pulmonary bleeding during life. This was suggested by the finding of massive haemosiderin deposits in the lung and a selectively and markedly elevated level of iron in trace element analysis of the lung tissue. Furthermore, we observed an enhanced deposition of birefringent particles in the lung tissue, without significant fibrosis. The histological analysis of liver, stomach and intestine confirmed the macroscopic organ diagnoses without evidence of any major pathological processes. In addition, analysis for various drugs revealed a significant deposition of tetrahydrocannabinol (THC), nicotine and cocaine in several organs of the mummy. The concentration profiles additionally provide evidence for a preferential inhalation of THC, while nicotine and cocaine containing drugs seem to have been consumed orally.
我们报告了一具经碳-14分析约可追溯至公元前950年的埃及木乃伊几个内脏器官的形态学和微量元素研究结果。通过采用多学科方法，我们成功发现了其生前严重且可能反复发生肺出血的证据。这一推断基于在肺部发现大量含铁血黄素沉积以及对肺组织进行微量元素分析时铁含量选择性且显著升高。此外，我们观察到肺组织中双折射颗粒沉积增加，但无明显纤维化。肝脏、胃和肠道的组织学分析证实了宏观器官诊断结果，未发现任何重大病理过程的迹象。此外，对多种药物的分析显示，木乃伊的多个器官中存在大量四氢大麻酚（THC）、尼古丁和可卡因沉积。浓度分布情况还进一步证明了对THC的优先吸入，而含尼古丁和可卡因的药物似乎是经口服摄入的。
