Albanese C T, Rowe M I
Department of Pediatric Surgery, Children's Hospital of Pittsburgh, PA 15213-2583, USA.
Semin Pediatr Surg. 1995 Nov;4(4):200-6.
Advances in neonatal care have resulted in an enlarging population of vulnerable premature newborns at risk for necrotizing enterocolitis (NEC). This article presents data supporting a unifying hypothesis for the initiation of NEC based on bacteria as the inciting agent(s), and the preterm baby as the vulnerable host. Facts and controversies concerning the pathology, microbiology, clinical presentation, management and outcome of infants afflicted with NEC are presented.
新生儿护理的进步导致了越来越多易患坏死性小肠结肠炎(NEC)的脆弱早产儿群体。本文提供的数据支持了一种关于NEC发病的统一假说,该假说认为细菌是引发因素,而早产儿是易感染宿主。文中介绍了有关NEC患儿的病理学、微生物学、临床表现、治疗及预后的事实与争议。