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丘脑前背侧核损伤大鼠的情绪反应与皮质肾上腺功能

Emotional response and corticoadrenal function in anterodorsal thalami nuclei lesioned rats.

作者信息

Dal Zotto S, Suárez M, Levin L, Perassi N

机构信息

Cátedra de Fisiología Animal, Facultad de Ciencias Exactas, Físicas y Naturales, Universidad Nacional de Córdoba, Argentina.

出版信息

Arch Physiol Biochem. 1995 Aug;103(4):497-501. doi: 10.3109/13813459509047145.

DOI:10.3109/13813459509047145
PMID:8548489
Abstract

In male and female rats, the effect of limbic anterodorsal thalami nuclei lesions (ADTN) on the emotional reactivity and their relationship with corticoadrenal function were studied. The emotional reactivity was evaluated by means of the open-field test and the corticoadrenal function by means of plasma anol adrenal corticosterone concentration. The results demonstrate that, on the 8th or 9th day after the lesion, the male rats show lack of habituation and the female ones, an increase in emotional reactivity. They also indicate that the lesion of ADTN does not affect the corticoadrenal response to exposure to novel situations.

摘要

在雄性和雌性大鼠中,研究了边缘前背侧丘脑核损伤(ADTN)对情绪反应性的影响及其与皮质-肾上腺功能的关系。通过旷场试验评估情绪反应性,通过血浆醛固酮和肾上腺皮质酮浓度评估皮质-肾上腺功能。结果表明,损伤后第8天或第9天,雄性大鼠表现出缺乏习惯化,而雌性大鼠的情绪反应性增加。结果还表明,ADTN损伤不影响皮质-肾上腺对新环境暴露的反应。

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