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土耳其中南部地区儿童脑膜炎球菌感染的流行病学

Epidemiology of meningococcal infections in children in mid-southern part of Turkey.

作者信息

Alhan E, Bozdemir N, Yüksel B, Onenli N, Kocabaş E, Aksaray N

机构信息

Department of Pediatrics, Faculty of Medicine, Cukurova University, Adana, Turkey.

出版信息

Eur J Epidemiol. 1995 Aug;11(4):393-6. doi: 10.1007/BF01721223.

Abstract

59 patients were treated for meningococcal infections in Cukurova University Faculty of Medicine, Division of Pediatric Infectious Diseases. 50.8% of patients were male, 33.9% were under two years of age and 61% were under five. 78% of patients were admitted to hospital in winter and spring time. Meningococcal meningitis (MM) was present in 39% of patients on admission, however, meningococcemia in 27.1% and meningococcemia and meningococcic meningitis (Meningococcemia + MM) in 33.9%. Fatality rate was 18.6% and no association was found between mortality and clinical type of disease (p > 0.05), but mortality ratio decreased with an increasing age (p < 0.01). No deaths occurred among the 12 patients who received i.v. penicillin treatment shortly before admitting to hospital, on the other hand 11 of 47 patients (23.4%) without such a previous treatment died.

摘要

59例脑膜炎球菌感染患者在库库罗瓦大学医学院儿科传染病科接受治疗。50.8%的患者为男性,33.9%的患者年龄在两岁以下,61%的患者年龄在五岁以下。78%的患者在冬季和春季入院。入院时,39%的患者患有脑膜炎球菌性脑膜炎(MM),27.1%的患者患有脑膜炎球菌血症,33.9%的患者患有脑膜炎球菌血症和脑膜炎球菌性脑膜炎(脑膜炎球菌血症+MM)。病死率为18.6%,未发现死亡率与疾病临床类型之间存在关联(p>0.05),但死亡率随着年龄的增长而降低(p<0.01)。在入院前不久接受静脉注射青霉素治疗的12例患者中无死亡病例,另一方面,47例未接受过此类治疗的患者中有11例(23.4%)死亡。

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