Serum lipid profile in children of coronary heart disease patients.

Serum lipid and lipoprotein cholesterol levels were analysed in 44 children from 5-14 years of age (index), belonging to 29 parents diagnosed as coronary artery disease (CAD). 314 children of parents without any CAD served as control. Index group had significantly (P < .05) higher levels of total cholesterol (Tch), triglycerides (TG) and very low density lipo-proteins cholesterol (VLDLc) and low levels of high density lipoprotein cholesterol (HDLc) (P < .05). Index group revealed higher levels of cholesterol, triglycerides and low density lipoprotein cholesterol in 31.8%, 6.8% and 36% cases respectively. HDLc did not show any significant variation. Index group whose parents had hypercholesteremia (Tch > 260 mg/dl) with CAD had raised levels of Tch, TG, LDLs and VLDLc when compared with control group (P < .05).