Eberl L, Christiansen G, Molin S, Givskov M
Department of Microbiology, Technical University of Denmark, Lyngby, Denmark.
J Bacteriol. 1996 Jan;178(2):554-9. doi: 10.1128/jb.178.2.554-559.1996.
The velocity with which a swarming colony of Serratia liquefaciens colonizes the surface of a suitable solid substratum was controlled by modulating the expression of the flhD master operon. In liquid medium, the stimulation of flhD expression resulted in filamentous, multinucleate, and hyperflagellated cells that were indistinguishable from swarm cells isolated from the edge of a swarm colony. Thus, expression of the flhD master operon appears to play a central role in the process of swarm cell differentiation.
通过调节flhD主操纵子的表达,可以控制液化沙雷氏菌群体在合适的固体基质表面定殖的速度。在液体培养基中,flhD表达的刺激导致丝状、多核和超鞭毛化的细胞,这些细胞与从群体菌落边缘分离的群体细胞无法区分。因此,flhD主操纵子的表达似乎在群体细胞分化过程中起着核心作用。