Kumagai E, Nakazono T, Niidome Y, Teshima M, Higashida A, Onomichi M, Kumagai T
Department of Medical Technology, College of Medical Science, Kumamoto University.
Rinsho Byori. 1995 Nov;43(11):1168-72.
An iron supplement was given to female blood donors to prevent iron deficiency after blood donation. The levels of items related to red blood cells and serum ferritin (S-Fer) among 17 iron-takers and 31 non-iron-takers were analyzed continuously. In most of the non-iron-takers, the S-Fer levels did not recover within four weeks after the donation of 200ml or 400ml of blood. In the approximately half of the donors, hemoglobin (Hb) levels did not recover either. However, in 59% of those taking iron supplements three times the amount of iron lost by donation, the levels of Hb and S-Fer recovered within two weeks. In the remaining 41%, the Hb levels recovered within four weeks by taking the iron supplement. Four weeks after blood donation, the incidence of iron deficiency anemia among the non-iron-takers increased from 13% to 23% and the incidence of latent iron deficiency among the non-iron-takers increased from 32% to 42%. However, the incidence of iron deficiency anemia among the iron-takers remained 0% and the incidence of latent iron deficiency among the iron-takers decreased from 12% to 6%.
给女性献血者补充铁剂以预防献血后缺铁。对17名服用铁剂者和31名未服用铁剂者的红细胞相关指标及血清铁蛋白（S-Fer）水平进行持续分析。在大多数未服用铁剂者中，捐献200毫升或400毫升血液后四周内S-Fer水平未恢复。在大约一半的献血者中，血红蛋白（Hb）水平也未恢复。然而，在服用的铁剂量为献血损失铁量三倍的人中，59%的人的Hb和S-Fer水平在两周内恢复。其余41%的人通过服用铁剂，Hb水平在四周内恢复。献血四周后，未服用铁剂者中铁缺乏性贫血的发生率从13%升至23%，未服用铁剂者中潜在缺铁的发生率从32%升至42%。然而，服用铁剂者中铁缺乏性贫血的发生率仍为0%，服用铁剂者中潜在缺铁的发生率从12%降至6%。
