Berrisford R G, Page R D, Donnelly R J
Cardiothoracic Centre, Liverpool, England.
J Thorac Cardiovasc Surg. 1996 Jan;111(1):142-6. doi: 10.1016/S0022-5223(96)70410-5.
An apparent reduction in the rate of benign anastomotic stricture after stapled esophagogastrectomy prompted us to review the results obtained with different stapling devices since 1988. We present a retrospective review of 125 consecutive patients undergoing esophageal resection for malignancy with stapled intrathoracic anastomoses. Benign anastomotic stricture was deemed present when a patient required endoscopic dilatation to treat postoperative dysphagia. We found no difference in risk factors not related to stapler size (tumor histologic characteristics, adjuvant therapy) between patients with stricture and patients without stricture. Event-free survival was compared for different stapler diameters as well as for different stapler designs. We found that staplers of smaller diameter were associated with significantly more strictures (p < 0.005). In a comparison of different designs of 25 mm stapler, the newer CDH device (Ethicon Ltd., Edinburgh, United Kingdom) was associated with a similar stricture rate to that associated with other designs (ILP [Ethicon] and EEA [Autosuture Company Division, United States Surgical Corp., Norwalk, Conn.]). For a given stapler diameter, it appears that different stapler designs have no effect on stricture rate.
吻合器行食管胃切除术后良性吻合口狭窄发生率明显降低,促使我们回顾自1988年以来使用不同吻合器的结果。我们对125例连续接受食管癌切除并在胸腔内行吻合器吻合的患者进行了回顾性研究。当患者需要内镜扩张治疗术后吞咽困难时,即认为存在良性吻合口狭窄。我们发现,吻合口狭窄患者与无狭窄患者之间,在与吻合器尺寸无关的危险因素(肿瘤组织学特征、辅助治疗)方面没有差异。我们比较了不同吻合器直径以及不同吻合器设计的无事件生存率。我们发现,直径较小的吻合器与明显更多的狭窄相关(p < 0.005)。在对25mm吻合器的不同设计进行比较时,较新的CDH装置(英国爱丁堡Ethicon有限公司)的狭窄发生率与其他设计(ILP [Ethicon]和EEA [美国外科公司诺沃克康涅狄格州Autosuture公司分部])相似。对于给定的吻合器直径,不同的吻合器设计似乎对狭窄发生率没有影响。