Rogers A, Nevill M
Occupational Hygiene Unit, Worksafe, NSW, Australia.
Scand J Work Environ Health. 1995 Aug;21(4):259-64. doi: 10.5271/sjweh.35.
The aim of the study was to review existing cases, calculate rates, and predict future numbers of occupational and environmental mesotheliomas from Wittenoom.
On the basis of information contained in occupational and environmental histories, Wittenoom cases were extracted from national records collected since 1979. Occupational and residential population estimates were obtained from company and government records. The proportional latency method was used to predict the numbers of mesotheliomas prior to and after the data collection phase. Airborne fiber monitoring was used to calculate risk due to current levels of contamination in the mine and town environments.
During 1979-1994, Wittenoom cases (N = 176) comprised approximately 6% of the mesothelioma cases recorded in Australia. Of these 122 were employed directly in the mining and milling activities, another 18 were involved in the transport of raw fiber or tailings, and 34 were town residents or visitors. Due to past exposures, additional occupational (N = 301) and environmental (N = 83) cases can be expected. Dependent on residential time, existing levels of contamination may result in a risk of between < 1 to 57 per million of the population.
Latency effects will result in considerable numbers of mesotheliomas appearing over the next 10-20 years in Wittenoom. The cessation of mining activities and major clean up of the town will result in reduced mesothelioma cases.
本研究旨在回顾现有病例，计算发病率，并预测来自维特努姆的职业性和环境性间皮瘤的未来病例数。
根据职业和环境病史中的信息，从1979年以来收集的国家记录中提取维特努姆病例。职业和居住人口估计数从公司和政府记录中获取。采用比例潜伏期法预测数据收集阶段之前和之后的间皮瘤病例数。通过空气纤维监测来计算由于矿山和城镇环境当前污染水平导致的风险。
在1979 - 1994年期间，维特努姆病例（N = 176）约占澳大利亚记录的间皮瘤病例的6%。其中122人直接受雇于采矿和选矿活动，另外18人参与原纤维或尾矿的运输，34人为城镇居民或访客。由于过去的接触，预计还会出现额外的职业性病例（N = 301）和环境性病例（N = 83）。根据居住时间的不同，现有的污染水平可能导致每百万人口中< 1至57的发病风险。
潜伏期效应将导致在未来10 - 20年维特努姆出现大量间皮瘤病例。采矿活动的停止和城镇的大规模清理将减少间皮瘤病例。
