Wulff M, Högberg U, Sandström A I
Department of Obstetrics and Gynaecology, University of Umeå, Sweden.
Scand J Work Environ Health. 1995 Aug;21(4):277-82. doi: 10.5271/sjweh.38.
The purpose of this study was to determine if emissions from a smelter affect the birthweight of offspring and increase the risk of prenatal death.
A historical cohort was formed from registers of birth and employees from 1961 to 1991. Comparisons of birthweight and perinatal deaths between children born to smelter employees or children born to women living around the smelter and those of a reference population were performed. To study reproductive effects before 1961, a case-referent study was performed with cases of stillbirths from 1937-1961 in one parish.
No differences in birthweight were found between the children born to employees or to people living near the smelter and those in the reference group. An increased risk of perinatal death among children born to women in the exposed group was seen during the period 1966-1970. However, for the rest of the observation period, 1961-1990, this higher risk was not apparent.
For the last 20 years emissions from the smelter had not affected the birthweight and the risk of perinatal death among the offspring of parents living near the smelter or those employed at the smelter.
本研究旨在确定冶炼厂排放物是否会影响后代的出生体重并增加产前死亡风险。
根据1961年至1991年的出生登记和员工登记信息组建了一个历史性队列。对冶炼厂员工的子女或居住在冶炼厂附近的女性所生子女与参照人群的出生体重和围产期死亡情况进行了比较。为研究1961年之前的生殖影响,在一个教区对1937年至1961年的死产病例进行了病例对照研究。
冶炼厂员工的子女或居住在冶炼厂附近的人的子女与参照组的出生体重没有差异。在1966年至1970年期间,暴露组女性所生子女的围产期死亡风险有所增加。然而,在1961年至1990年的其余观察期内,这种较高风险并不明显。
在过去20年里,冶炼厂的排放物并未影响居住在冶炼厂附近的父母或在冶炼厂工作的父母的后代的出生体重和围产期死亡风险。