铝冶炼厂男工和女工的生殖结果。
Reproductive outcomes among male and female workers at an aluminum smelter.
机构信息
Department of Occupational Medicine and Environmental Health, Yale University School of Medicine, New Haven, CT, USA.
出版信息
J Occup Environ Med. 2010 Feb;52(2):137-43. doi: 10.1097/JOM.0b013e3181cb59bc.
OBJECTIVES
Several adverse pregnancy outcomes were reported among female laboratory workers in a North American aluminum smelter. To determine whether these outcomes were associated with any occupational exposure at the plant, a cross-sectional survey was undertaken.
METHODS
Rates of miscarriage, premature singleton birth, and major congenital anomaly occurring during employment were compared with a reference group comprised of all pregnancies that occurred before employment.
RESULTS
Among female workers, the excess of congenital anomalies among female laboratory workers that defined the initial cluster was observed, but no specific pattern was found.
CONCLUSIONS
On the basis of these analyses, the increase in congenital anomalies could not be attributed to occupational exposures at the smelter nor could potential exposure likely explain the diverse anomalies described.
目的
在北美一家铝冶炼厂的女性实验室工作者中报告了几种不良妊娠结局。为了确定这些结局是否与工厂的任何职业暴露有关，进行了一项横断面调查。
方法
将在职期间发生的流产、早产和主要先天畸形的发生率与由所有在就业前发生的妊娠组成的参考组进行比较。
结果
在女性工人中，最初的聚集定义了女性实验室工人中先天畸形的过量，但没有发现特定的模式。
结论
基于这些分析，先天畸形的增加不能归因于冶炼厂的职业暴露，潜在的暴露也不太可能解释所描述的不同的异常。
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