Petersen M M, Nielsen P T, Lauritzen J B, Lund B
Department of Orthopedics U 2161, Rigshospitalet, University of Copenhagen, Denmark.
Acta Orthop Scand. 1995 Dec;66(6):513-6. doi: 10.3109/17453679509002305.
We measured bone remodeling of the proximal tibia prospectively for 3 years after uncemented total knee arthroplasty (TKA) in 25 knees with primary arthrosis. In the trabecular bone below the tibial component, bone mineral density (BMD) was measured in 6 different regions of interest (ROI), using dual photon absorptiometry (DPA). In the tibial condyles, where the change in knee alignment indicated that the load was reduced postoperatively, a fast bone loss of 7-20% was seen during the first 6 months after surgery. A small, but significant increase in BMD of 2-7% was seen in the tibial condyles, where the load was increased. On average, the density for all ROI below the tibial component showed a significant and progressive decrease in BMD, reaching 22% at 3 years follow-up.
我们对25例原发性骨关节炎患者的25个膝关节在进行非骨水泥型全膝关节置换术（TKA）后，前瞻性地测量了胫骨近端的骨重塑情况，为期3年。在胫骨假体下方的小梁骨中，使用双能光子吸收法（DPA）在6个不同的感兴趣区域（ROI）测量骨矿物质密度（BMD）。在胫骨髁，膝关节对线的改变表明术后负荷降低，术后前6个月出现了7%-20%的快速骨质流失。在负荷增加的胫骨髁，BMD有2%-7%的小幅但显著增加。平均而言，胫骨假体下方所有ROI的密度显示BMD显著且逐渐降低，在3年随访时达到22%。
