Mitler M M, Van den Hoed J, Carskadon M A, Richardson G, Park R, Guilleminault C, Dement W C
Electroencephalogr Clin Neurophysiol. 1979 Apr;46(4):479-81. doi: 10.1016/0013-4694(79)90149-4.
Forty narcoleptic patients were given the Multiple Sleep Latency Test, consisting of 20 min opportunities to sleep offered at 10.00, 12.00, 14.00, 16.00 and 18.00 o'clock. Eleven patients had 2 episodes of REM sleep, 5 had 3, 11 had 4, and 13 had 5 before they were awakened. Fourteen control subjects given similar opportunities to sleep (reported in a companion article (Richardson et al. 1978)) had no REM sleep episodes. For the 10.00-18.00 o'clock opportunities respectively, there were 32, 29, 30, 28 and 27 REM sleep episodes. We conclude that this procedure can provide physicians with data useful in the diagnosis of narcolepsy.
40名发作性睡病患者接受了多次睡眠潜伏期测试,测试包括在上午10点、12点、下午2点、4点和6点提供20分钟的睡眠时间。11名患者在被唤醒前有2次快速眼动睡眠发作,5名患者有3次,11名患者有4次,13名患者有5次。14名对照受试者有类似的睡眠时间(在一篇相关文章中报道(理查森等人,1978年)),但没有快速眼动睡眠发作。在上午10点至下午6点的睡眠时间里,快速眼动睡眠发作次数分别为32次、29次、30次、28次和27次。我们得出结论,该测试程序可为医生提供有助于发作性睡病诊断的数据。