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[隐睾症与睾丸癌]

[Cryptorchidism and testicular cancer].

作者信息

Pereira Arias J G, Astobieta Odriozola A, Zabalza Estévez I, Bernuy Malfaz C

机构信息

Servicio de Urología, Hospital de Galdakao, Vizcaya, España.

出版信息

Arch Esp Urol. 1995 Nov;48(9):959-61.

PMID:8554405
Abstract

OBJECTIVE

This report underscores the higher risk of testicular cancer in cryptorchidism.

METHODS/RESULTS: A patient undergoing evaluation for sterility, who was submitted to orchidopexy 15 years earlier for cryptorchidism, developed a seminoma-like tumor one year following a testicular biopsy that was compatible with testicular atrophy, but with no signs of dysplasia. The literature on the epidemiology, pathogenesis, diagnosis, and treatment is briefly reviewed.

CONCLUSIONS

Cryptorchidism is the single factor that carries a higher risk of testicular cancer. This condition has been reported to have 3.5 to 5 times greater risk of progressing to malignancy compared to normal descended testes. Although orchiopexy does not prevent the risk of malignancy, it permits earlier detection. The need to follow these patients closely is underscored.

摘要

目的

本报告强调隐睾症患者患睾丸癌的风险更高。

方法/结果:一名因不育接受评估的患者,15年前因隐睾症接受了睾丸固定术,在一次与睾丸萎缩相符但无发育异常迹象的睾丸活检一年后,患上了类似精原细胞瘤的肿瘤。本文简要回顾了有关流行病学、发病机制、诊断和治疗的文献。

结论

隐睾症是导致睾丸癌风险较高的唯一因素。据报道,与正常下降的睾丸相比,这种情况发展为恶性肿瘤的风险要高3.5至5倍。虽然睾丸固定术不能预防恶性肿瘤的风险,但它能使早期检测成为可能。强调了对这些患者进行密切随访的必要性。

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