Klijnsma M P, Cameron M L, Burns T P, McGuigan S M
Springfield Hospital, London, UK.
Alcohol Alcohol. 1995 Sep;30(5):669-73.
We assessed the outcome after 2 months of 28 alcohol-dependent subjects following out-patient detoxification using an uncontrolled follow-up study with data collected at the time of detoxification (T1) and after 2 months (T2). We also determined the cost of out-patient versus in-patient detoxification. The setting was a psychiatric emergency clinic at a South West London University Hospital. Self-reported alcohol consumption in the week before T1 and T2, score on the 'Alcohol Problems Inventory' measuring alcohol-related relational, occupation, legal and medical problems in the 2 months prior to T1 and T2, mean corpuscular volume and gamma-glutamyl transferase at T1 and T2 were used as outcome measures. Eight subjects had a 'good' outcome (seven were abstinent and one only drank four units on one day). Nine subjects were 'improved' by either having their alcohol consumption, or halving their 'Alcohol Problems Inventory' score at T2. 'Good' and 'improved' outcome were confirmed by mean corpuscular volume and gamma-glutamyl transferase results. Eleven subjects were 'not improved'. Engagement following detoxification with voluntary alcohol agencies was associated with a better outcome. In-patient detoxification is calculated to be six times more expensive than out-patient detoxification. Out-patient detoxification is a cost-effective step in the treatment of alcohol-dependent patients.
我们采用一项无对照的随访研究，对28名酒精依赖患者门诊脱毒2个月后的结果进行了评估，在脱毒时（T1）和2个月后（T2）收集数据。我们还确定了门诊与住院脱毒的费用。研究地点为伦敦西南部一家大学医院的精神科急诊诊所。将T1和T2前一周的自我报告饮酒量、在T1和T2前两个月测量与酒精相关的人际关系、职业、法律和医疗问题的“酒精问题量表”得分、T1和T2时的平均红细胞体积和γ-谷氨酰转移酶作为结果指标。8名患者获得“良好”结果（7人戒酒，1人仅在某一天饮酒4个单位）。9名患者“有所改善”，即要么饮酒量减少，要么在T2时“酒精问题量表”得分减半。平均红细胞体积和γ-谷氨酰转移酶结果证实了“良好”和“有所改善”的结果。11名患者“未改善”。脱毒后与志愿戒酒机构接触与更好的结果相关。住院脱毒的费用经计算比门诊脱毒贵6倍。门诊脱毒是治疗酒精依赖患者的一个具有成本效益的步骤。
