Moore C S, Cheong I
Department of Medicine, University Kebangsaan Malaysia, Kuala Lumpur.
Br J Clin Pract. 1995 Nov-Dec;49(6):304-7.
The clinical, haematological and biochemical profiles of all domestic and imported malaria cases admitted to the Hospital Kuala Lumpur were analysed. The most common malaria types were Plasmodium falciparum (39.5%) and Plasmodium vivax (42%). The most common patient type was men aged 29-40 years (reflecting the high mobility of this group, many of whom were illegal immigrants). Misdiagnosis on admission was frequently due to the variable clinical presentation of the disease and the difficulties of obtaining an accurate history. Associated haematological abnormalities were common. Chloroquine resistance was diagnosed in four P. falciparum patients and in one P. falciparum/vivax patient. Overall, imported malaria did not seem more severe than domestic. The three patients with cerebral malaria survived. One patient died of acute liver failure. The large influx of illegal immigrants to Malaysia has resulted in a surge in malaria infection; illegal immigrants remain a source of chloroquine resistance.
对吉隆坡医院收治的所有本地和输入性疟疾病例的临床、血液学和生化特征进行了分析。最常见的疟疾类型是恶性疟原虫（39.5%）和间日疟原虫（42%）。最常见的患者类型是29至40岁的男性（这反映了该群体的高流动性，其中许多是非法移民）。入院时的误诊经常是由于疾病临床表现的多样性以及获取准确病史的困难。相关的血液学异常很常见。在4例恶性疟原虫患者和1例恶性疟原虫/间日疟原虫患者中诊断出氯喹耐药。总体而言，输入性疟疾似乎并不比本地疟疾更严重。3例脑型疟患者存活。1例患者死于急性肝衰竭。大量非法移民涌入马来西亚导致疟疾感染激增；非法移民仍然是氯喹耐药的一个来源。
