Ignat'eva E N
Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(3):352-6.
The absence of an ependimic layer in cases of syringomyelia described in literature and in the author's own studies, the dislocation of cavities on the background of formted gray matter, the structure of the edge of the cavity, as well as sclerosis, a gyalinosis of vessels and fibrosis of the meninx--all these phenomena confirm the opinion of syringomyelitic cavities as an acquired defect and not dysraphia. A comparative study of the morphogenesis of medullar cavities in inflammatory, vascular, traumatical processes and in syringomyelia permits to mark their histological similarity and postnecrotic genesis. The glyosis in syringomyelitic cavities has a different character. The fibrillar glyosis along the edge of the cavities appears due to reparative changes and plays a delineating role. Irritative glyosis appears more frequently in angiomatosis, accompanied by chronic microhemorrhages. Expressed glyosis with a formation of cellular rosettes is to a certain extent a tumor (astrocytomaa, epeudimoma), while a syringomyelitic cavity--a histiolytic cyst of a tumor.
文献及作者自身研究中所描述的脊髓空洞症病例中缺乏室管膜层、在形成的灰质背景下空洞的移位、空洞边缘的结构，以及硬化、血管玻璃样变性和脑膜纤维化——所有这些现象都证实了脊髓空洞症空洞是后天性缺陷而非神经管闭合不全的观点。对炎症、血管、创伤性过程及脊髓空洞症中髓腔形态发生的比较研究，有助于明确它们的组织学相似性及坏死后期发生机制。脊髓空洞症空洞中的玻璃样变性具有不同特点。空洞边缘的纤维状玻璃样变性是修复性改变的结果，起界定作用。刺激性玻璃样变性在血管瘤病中更常见，伴有慢性微出血。出现细胞玫瑰花结形成的明显玻璃样变性在一定程度上是肿瘤（星形细胞瘤、室管膜瘤），而脊髓空洞症空洞是肿瘤的组织溶解性囊肿。
