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男性的认知偏差任务与额叶功能偏侧化

The Cognitive Bias Task and lateralized frontal lobe functions in males.

作者信息

Podell K, Lovell M, Zimmerman M, Goldberg E

机构信息

Department of Psychiatry, Medical College of Pennsylvania, Pittsburgh, USA.

出版信息

J Neuropsychiatry Clin Neurosci. 1995 Fall;7(4):491-501. doi: 10.1176/jnp.7.4.491.

DOI:10.1176/jnp.7.4.491
PMID:8555753
Abstract

The Cognitive Bias Task (CBT) is a multiple-choice response selection paradigm characterized by inherent ambiguity. All items offer a range from extremely context-dependent to extremely context-invariant responses. Lateralized prefrontal lesions produce extreme, and opposite, response biases on CBT in right-handed males. Healthy control subjects perform in the middle range. Findings suggest a dynamic balance between two synergistic decision-making systems in the frontal lobes: context-dependent in the left hemisphere and context-invariant in the right. The robust lateralized effects, which are dependent on task ambiguity, are sensitive and specific to frontal dysfunction. CBT is discussed in comparison with the Wisconsin Card Sorting Test as a potential cognitive activation task for functional neuroimaging of the frontal lobes.

摘要

认知偏差任务(CBT)是一种以固有模糊性为特征的多项选择反应选择范式。所有项目都提供了从极度依赖情境到极度不依赖情境的反应范围。右侧前额叶病变在右利手男性的CBT中会产生极端且相反的反应偏差。健康对照受试者的表现处于中等范围。研究结果表明,额叶中两个协同决策系统之间存在动态平衡:左半球依赖情境,右半球不依赖情境。这种强大的偏侧化效应依赖于任务的模糊性,对额叶功能障碍敏感且具有特异性。本文将CBT与威斯康星卡片分类测试进行了比较,讨论了其作为额叶功能神经成像潜在认知激活任务的情况。

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