New York University School of Medicine, New York.
J Cogn Neurosci. 1994 Summer;6(3):276-96. doi: 10.1162/jocn.1994.6.3.276.
Abstract Performance of patients with quadrant lesions on the inherently ambiguous Cognitive Bias Task (CBT) suggests sexual dimorphism in the fundamental aspects of functional cortical geometry, by emphasizing different cerebral axes. In right-handed males, extreme context-dependent and context-independent response selection biases are reciprocally linked to left vs. right frontal systems. In right-handed females, these complementary biases appear to be reciprocally linked to posterior vs. frontal cortices. Frontal lobe functions are more lateralized in males than females due to sexual dimorphism of the left frontal systems. Both in males and females, patterns of CBT scores in non-right-handers with quadrant lesions are opposite to those found in right-handers. This suggests the existence of two functionally and neurally distinct cognitive selection mechanisms. Both mechanisms involve the frontal lobes, but their exact neuroanatomy depends on sex and handedness.
摘要 象限病变患者在固有歧义的认知偏差任务（CBT）上的表现表明，在功能皮质几何的基本方面存在性别二态性，强调了不同的大脑轴。在右利手男性中，极端的情境依赖和情境独立的反应选择偏差与左、右额系统相互关联。在右利手女性中，这些互补的偏差似乎与后、额皮质相互关联。由于左侧额系统的性别二态性，男性的额叶功能比女性更偏侧化。在非右利手的象限病变患者中，CBT 评分模式与右利手患者相反。这表明存在两种功能和神经上不同的认知选择机制。这两种机制都涉及额叶，但它们的确切神经解剖结构取决于性别和利手性。
