Harrison B M
Acta Neuropathol. 1977 Apr 29;38(1):33-8. doi: 10.1007/BF00691273.
The Trembler mouse suffers from an hereditary demyelinating neuropathy. Schwann cell myelination of peripheral nerve fibres in the Trembler mouse is abnormal. Myelination of central nerve fibres in the deeper layers of white matter of the spinal cord is normal. At the junction between the peripheral nervous system and the central nervous system in the ventral roots in the Trembler mouse central-type nerve fibres are abnormally thinly myelinated. It is suggested that the normal process of myelination of central nerve fibres in this region is affected by abnormalities of the Schwann cell in the peripheral nervous system.
颤抖鼠患有遗传性脱髓鞘性神经病变。颤抖鼠外周神经纤维的施万细胞髓鞘形成异常。脊髓白质深层的中枢神经纤维髓鞘形成正常。在颤抖鼠腹根处的外周神经系统与中枢神经系统的交界处，中枢型神经纤维的髓鞘异常薄。有人认为，该区域中枢神经纤维正常的髓鞘形成过程受到外周神经系统中施万细胞异常的影响。
