Uvnäs-Wallensten K, Andersson H
Acta Physiol Scand. 1977 Apr;99(4):496-502. doi: 10.1111/j.1748-1716.1977.tb10403.x.
Gastrin release and HCl secretion was induced by electrical vagal stimulation in anesthetized cats. Both atropine (0.1-0.3 mg/kg) and methiamide (4-20 mg/kg) inhibited the HCl secretion (by approximately 60 and approximately 80 %). On the other hand, neither atropine (0.2-2 mg/kg) nor methiamide (20 mg/kg) inhibited the vagally induced gastrin release. Possible explanations of the atropine resistance of the vagal gastrin release mechanism are discussed.
在麻醉猫中，电刺激迷走神经可诱导胃泌素释放和盐酸分泌。阿托品（0.1 - 0.3毫克/千克）和甲硫酰胺（4 - 20毫克/千克）均抑制盐酸分泌（分别约抑制60%和约80%）。另一方面，阿托品（0.2 - 2毫克/千克）和甲硫酰胺（20毫克/千克）均不抑制迷走神经诱导的胃泌素释放。文中讨论了迷走神经胃泌素释放机制对阿托品产生抗性的可能解释。
