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甲硫米特抑制假饲诱发的犬胃酸分泌。

Metiamide inhibits canine gastric acid secretion evoked by sham feeding.

作者信息

Sjödin L

出版信息

Scand J Gastroenterol. 1976;11(6):559-60.

PMID:981959
Abstract

A continuous intravenous infusion of metiamide markedly inhibited the gastric acid secretory response to sham feeding in two dogs provided with Pavlov pouches and gastric fistulae. The results show that an antagonist of histamine H2-receptors is capable of inhibiting a vagally activated secretion evoked by sham feeding, which may be considered a physiological vagal stimulus.

摘要

对两只设有巴甫洛夫小胃和胃瘘的狗持续静脉输注甲硫米特,可显著抑制假饲引起的胃酸分泌反应。结果表明,组胺H2受体拮抗剂能够抑制假饲诱发的迷走神经激活分泌,假饲可被视为一种生理性迷走神经刺激。

相似文献

1
Metiamide inhibits canine gastric acid secretion evoked by sham feeding.甲硫米特抑制假饲诱发的犬胃酸分泌。
Scand J Gastroenterol. 1976;11(6):559-60.
2
Effect of the H2-receptor antagonists (burimamide and metiamide) on gastric secretion stimulated by histamine and its methyl derivatives.H2受体拮抗剂(布立马胺和甲硫米特)对组胺及其甲基衍生物刺激的胃酸分泌的影响。
J Pharmacol Exp Ther. 1975 May;193(2):614-20.
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Effect of atropine and methiamide on vagally induced gastric acid secretion and gastrin release in anesthetized cats.阿托品和甲硫米特对麻醉猫迷走神经诱导的胃酸分泌和胃泌素释放的影响。
Acta Physiol Scand. 1977 Apr;99(4):496-502. doi: 10.1111/j.1748-1716.1977.tb10403.x.
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Action of somatostatin and metiamide on gastric acid secretion from isolated bullfrog gastric mucosa.生长抑素和甲硫咪胺对离体牛蛙胃黏膜胃酸分泌的作用。
Res Commun Chem Pathol Pharmacol. 1976 Jan;13(1):149-52.
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Inhibition of gastrin-stimulated canine acid secretion by sham-feeding.假饲对胃泌素刺激的犬胃酸分泌的抑制作用。
Scand J Gastroenterol. 1975;10(1):73-80.
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Effects of metiamide, a histamine H2-receptor antagonist, on vagally induced gastric secretion in dogs.组胺H2受体拮抗剂甲硫米特对犬迷走神经诱导的胃液分泌的影响。
Surg Forum. 1974;25(0):319-21.
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Effect of histamine H2 antagonism by metiamide on the response of the canine gastric mucosa to acid and bile salt.甲硫米特对组胺H2的拮抗作用对犬胃黏膜对酸和胆盐反应的影响。
Gastroenterology. 1977 Aug;73(2):255-9.
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Gastric secretion during anaesthesia and its inhibition by metiamide and other drugs.麻醉期间的胃液分泌及其受甲硫米特和其他药物的抑制作用。
Experientia. 1975 Aug 15;31(8):964-5. doi: 10.1007/BF02358879.
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Proceedings: Effect of H2-receptor blockade on vagally induced gastric secretion and gastric emptying in man.论文集:H2受体阻断对人体迷走神经诱导的胃液分泌和胃排空的影响
Gut. 1974 Apr;15(4):337.
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Effect of the H2-receptor antagonist metiamide on carbachol- and histamine-induced gastric acid secretion in the Atlantic cod,Gadus morhua.H2受体拮抗剂甲硫米特对大西洋鳕鱼(Gadus morhua)中卡巴胆碱和组胺诱导的胃酸分泌的影响。
Acta Physiol Scand. 1976 Jun;97(2):189-95. doi: 10.1111/j.1748-1716.1976.tb10251.x.

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Inhibitory effect of cimetidine on gastric acid secretion vagally activated by physiological means in duodenal ulcer patients.西咪替丁对十二指肠溃疡患者经生理途径迷走神经激活所致胃酸分泌的抑制作用。
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