[Fetal fibronectin diagnosis of premature rupture of the amniotic membranes].

OBJECTIVE

To determine whether fetal fibronectin is a sensitive test for the detection of premature rupture of the amniotic membranes.

METHODS

Fetal fibronectin by ABC immunoblotting methods were measured in samples of cervicovaginal secretion from 80 cases with ruptured amniotic membranes (study group) and 50 cases of term pregnancy (control group A). Plasma fetal fibronectin were examined in 30 cases of normal pregnancy (control group B).

RESULTS

The detection rate of fetal fibronectin in the women with ruptured membranes was 95.0%, While 6% in normal pregnancy.

CONCLUSIONS

Fetal fibronectin is a sensitive test for detection of present of amniotic fluid. It can be used for diagnosis of ruptured amniotic membranes.