[羊膜早破的胎儿纤连蛋白诊断]
[Fetal fibronectin diagnosis of premature rupture of the amniotic membranes].
作者信息
Gu H, Ding Y, Li Y
机构信息
Changhai Hospital, Second Military Medical University, Shanghai.
出版信息
Zhonghua Fu Chan Ke Za Zhi. 1995 Sep;30(9):533-5.
OBJECTIVE
To determine whether fetal fibronectin is a sensitive test for the detection of premature rupture of the amniotic membranes.
METHODS
Fetal fibronectin by ABC immunoblotting methods were measured in samples of cervicovaginal secretion from 80 cases with ruptured amniotic membranes (study group) and 50 cases of term pregnancy (control group A). Plasma fetal fibronectin were examined in 30 cases of normal pregnancy (control group B).
RESULTS
The detection rate of fetal fibronectin in the women with ruptured membranes was 95.0%, While 6% in normal pregnancy.
CONCLUSIONS
Fetal fibronectin is a sensitive test for detection of present of amniotic fluid. It can be used for diagnosis of ruptured amniotic membranes.
目的
确定胎儿纤连蛋白是否是检测胎膜早破的敏感试验。
方法
采用ABC免疫印迹法测定80例胎膜破裂患者（研究组）和50例足月妊娠患者（对照组A）宫颈阴道分泌物样本中的胎儿纤连蛋白。检测30例正常妊娠患者（对照组B）血浆中的胎儿纤连蛋白。
结果
胎膜破裂患者胎儿纤连蛋白的检出率为95.0%，而正常妊娠患者为6%。
结论
胎儿纤连蛋白是检测羊水存在的敏感试验。可用于诊断胎膜破裂。
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