Cherian B P, Mathai E, Chandy S
Department of Microbiology, Christian Medical College & Hospital, Vellore.
Indian J Med Res. 1995 Dec;102:255-7.
Two hundred and ten strains of enterococci showing resistance to gentamicin (10 micrograms/disc) were tested for high level resistance by detecting the minimum inhibitory concentration and by using high content disc diffusion test. Only 67 per cent of these had high level resistance to gentamicin. High level kanamycin resistance in the group was 84 per cent, while high level streptomycin resistance was 61 per cent. Only 85 of the 140 strains with high level gentamicin resistance had similar streptomycin resistance. Results using locally made high content discs, correlated 100 per cent with MIC results. High level resistance to enterococci should be reported on a routine basis, especially when isolated from patients with serious infections.
对210株对庆大霉素（10微克/纸片）耐药的肠球菌进行了高水平耐药检测，检测方法为测定最低抑菌浓度和使用高含量纸片扩散试验。其中只有67%的菌株对庆大霉素具有高水平耐药性。该组中高水平卡那霉素耐药率为84%，而高水平链霉素耐药率为61%。在140株对庆大霉素具有高水平耐药性的菌株中，只有85株具有相似的链霉素耐药性。使用本地生产的高含量纸片得出的结果与最低抑菌浓度结果的相关性为100%。应常规报告肠球菌的高水平耐药情况，尤其是从严重感染患者中分离出的菌株。
