Kumamoto Y, Hirose T, Tanaka N, Hikichi Y, Shigeta S, Shiraiwa Y, Kameoka H, Yoshida H, Ogata M, Tazaki H
Department of Urology, School of Medicine, Sapporo Medical College.
Jpn J Antibiot. 1995 Oct;48(10):1317-28.
Clinical background was investigated on 861 bacterial strains isolated from patients with urinary tract infections (UTIs) in 10 hospitals during the period from June, 1990 to May, 1991. 1. Distribution of sex, age and infections: Among over fifties males, the complicated urinary tract infections was most frequent. Among females, the uncomplicated urinary tract infections was most frequent without a relation of age. 2. Distribution of sex, age and pathogens isolated from UTIs: In uncomplicated UTIs, Escherichia coli was most frequently isolated without a relation of age. In complicated UTIs without indwelling catheter, E. coli and Enterococcus faecalis were isolated with a frequency of 20-30%, respectively. In complicated UTIs with indwelling catheter, Pseudomonas aeruginosa were most frequently isolated, and next E. faecalis. 3. Administration of antibiotics and pathogens isolated from UTIs: In uncomplicated UTIs and complicated UTIs without indwelling catheter, pathogens, after administration of antibiotics, isolated from patients have obviously decreased. In complicated UTIs with indwelling catheter, pathogens, before and after administration of antibiotics, isolated from patients were not decreased. And the distribution of pathogens after administration of antibiotics was similar.
对1990年6月至1991年5月期间从10家医院的尿路感染(UTIs)患者中分离出的861株细菌菌株进行了临床背景调查。1. 性别、年龄和感染分布:在50岁以上男性中,复杂性尿路感染最为常见。在女性中,非复杂性尿路感染最为常见,且与年龄无关。2. 从UTIs分离出的性别、年龄和病原体分布:在非复杂性UTIs中,大肠埃希菌最常被分离出,且与年龄无关。在无留置导管的复杂性UTIs中,大肠埃希菌和粪肠球菌的分离频率分别为20% - 30%。在有留置导管的复杂性UTIs中,铜绿假单胞菌最常被分离出,其次是粪肠球菌。3. 抗生素使用情况与从UTIs分离出的病原体:在非复杂性UTIs和无留置导管的复杂性UTIs中,使用抗生素后从患者分离出的病原体明显减少。在有留置导管的复杂性UTIs中,使用抗生素前后从患者分离出的病原体没有减少。且使用抗生素后病原体的分布相似。