[1991年抗菌药物对尿路感染分离病原菌活性的比较研究。II. 患者背景]
[Comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1991). II. Background of patients].
作者信息
Kumamoto Y, Hirose T, Tanaka N, Hikichi Y, Shigeta S, Shiraiwa Y, Kameoka H, Yoshida H, Ogata M, Tazaki H
机构信息
Department of Urology, School of Medicine, Sapporo Medical College.
出版信息
Jpn J Antibiot. 1995 Oct;48(10):1422-35.
Clinical background was investigated on 632 bacterial strains isolated from patients with urinary tract infections (UTIs) in 11 hospitals during the period from June, 1991 to May, 1992. 1. Distribution of sex, age and infections Among over forties males, the majority was taken by complicated urinary tract infections. Among females, the uncomplicated urinary tract infections was most frequent without a relation of age. 2. Distribution of sex, age and pathogens isolated from UTIs In uncomplicated UTIs, Escherichia coli was most frequently isolated without a relation of age, and next Enterococcus faecalis in over fifties. In complicated UTIs without indwelling catheter, E. coli and E. faecalis were isolated with a frequency of 17.4-26.6%, respectively. In complicated UTIs with indwelling catheter, E. faecalis were most frequently isolated, and next Pseudomonas aeruginosa. 3. Administration of antibiotics and pathogens isolated from UTIs In uncomplicated UTIs, pathogens, after administration of antibiotics, isolated from patients have obviously decreased from 319 to 34 isolates. And also, pathogens of complicated UTIs without indwelling catheter, have decreased from 122 to 49 isolates. However, in complicated UTIs with indwelling catheter, pathogens after or before administration of antibiotics, were not revealed an obvious change. 4. Pathogens and UTIs with or without factor and operation In uncomplicated UTIs with or without factor and operation, E. coli was mainly detected. In complicated UTIs without indwelling catheter and with or without factor and operation, E. faecalis and E. coli were mainly detected. In complicated UTIs with indwelling catheter and with factor and operation, E. faecalis and P. aeruginosa were detected, 24.3% and 22.9%, respectively. Without factor and operation, E. faecalis was detected 18.4%, and next Klebsiella spp. 15.8%. And the distribution of pathogens after administration of antibiotics was similar.
对1991年6月至1992年5月期间从11家医院的尿路感染（UTIs）患者中分离出的632株细菌菌株进行了临床背景调查。1. 性别、年龄和感染分布 在40岁以上男性中，大多数为复杂性尿路感染。在女性中，非复杂性尿路感染最为常见，与年龄无关。2. 从UTIs中分离出的性别、年龄和病原体分布 在非复杂性UTIs中，大肠杆菌最常被分离出，与年龄无关，其次是50岁以上的粪肠球菌。在无留置导管的复杂性UTIs中，大肠杆菌和粪肠球菌的分离频率分别为17.4 - 26.6%。在有留置导管的复杂性UTIs中，粪肠球菌最常被分离出，其次是铜绿假单胞菌。3. 抗生素使用情况与从UTIs中分离出的病原体 在非复杂性UTIs中，使用抗生素后，从患者中分离出的病原体明显从319株减少到34株。同样地，无留置导管的复杂性UTIs的病原体也从122株减少到49株。然而，在有留置导管的复杂性UTIs中，使用抗生素前后的病原体没有明显变化。4. 病原体与有无因素及手术的UTIs 在有无因素及手术的非复杂性UTIs中，主要检测到大肠杆菌。在无留置导管且有无因素及手术的复杂性UTIs中，主要检测到粪肠球菌和大肠杆菌。在有留置导管且有因素及手术的复杂性UTIs中，分别检测到粪肠球菌和铜绿假单胞菌，比例分别为24.3%和22.9%。在无因素及手术的情况下，检测到粪肠球菌的比例为18.4%，其次是克雷伯菌属，为15.8%。使用抗生素后病原体的分布情况相似。
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