George A O, Malabu U H, Olubuyide I O
Dermatology Unit, University College Hospital, Ibadan, Nigeria.
Trop Geogr Med. 1995;47(4):168-70.
Sixty negroid patients with liver cirrhosis were examined for their cutaneous features at the University College Hospital, Ibadan, Nigeria. When compared with age and sex matched controls, the cirrhotic patients had significantly lower body temperature, onycholysis and hyperpigmented palmo-plantar macular areas (p < 0.05). Until now, these features have not been previously associated with liver cirrhosis. Other cutaneous signs such as sparse silky hair, female public hair pattern, digital clubbing, leuconychia, ankle oedema and corneal jaundice are found more commonly in cirrhotic patients (p < 0.05) and have been previously documented. All these features in a middle-aged man with hepatomegaly may be of added distinctive value particularly in many rural centres in tropical countries where facilities for definitive histological diagnosis are frequently lacking. The relevance of some of these cutaneous features in the light of the pattern described in Caucasians is also discussed.
在尼日利亚伊巴丹大学学院医院，对60名患有肝硬化的黑人患者的皮肤特征进行了检查。与年龄和性别匹配的对照组相比，肝硬化患者的体温显著较低，出现了甲剥离和掌跖色素沉着斑区（p < 0.05）。到目前为止，这些特征以前尚未与肝硬化相关联。其他皮肤体征，如毛发稀疏如丝、女性阴毛分布模式、杵状指、白甲、踝关节水肿和角膜黄疸，在肝硬化患者中更常见（p < 0.05），并且以前已有文献记载。在一名患有肝肿大的中年男性身上出现的所有这些特征可能具有额外的独特价值，特别是在热带国家的许多农村地区，那里经常缺乏进行明确组织学诊断的设施。还讨论了根据白种人所描述的模式，其中一些皮肤特征的相关性。
