Jarow J P, Coburn M, Sigman M
Department of Urology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina 27106, USA.
Urology. 1996 Jan;47(1):73-6. doi: 10.1016/s0090-4295(99)80385-9.
To determine whether varicoceles are more prevalent in men with secondary infertility than in men with primary infertility.
The records of 2188 consecutive men attending three infertility centers were reviewed to determine the incidence of varicoceles in men with primary and secondary infertility. In addition, other factors affecting both male and female infertility were assessed in these patients.
The incidence of varicoceles was not significantly different between the 1447 men with primary infertility versus the 741 men with secondary infertility: 44% and 45%, respectively. The incidence of vasal agenesis was significantly greater in men with primary infertility (P < 0.001). In addition, the female partner was significantly older in couples with secondary infertility (P < 0.001).
These findings do not support the conclusion that varicoceles have a progressive adverse effect on fertility over time and suggest that further study is needed to determine whether varicocele repair is indicated in patients with normal semen parameters.
确定精索静脉曲张在继发性不育男性中是否比原发性不育男性更普遍。
回顾了三个不育症中心连续就诊的2188名男性的记录，以确定原发性和继发性不育男性中精索静脉曲张的发生率。此外，还评估了这些患者中影响男性和女性不育的其他因素。
1447名原发性不育男性与741名继发性不育男性的精索静脉曲张发生率无显著差异，分别为44%和45%。原发性不育男性中输精管缺如的发生率显著更高（P<0.001）。此外，继发性不育夫妇中女性伴侣的年龄显著更大（P<0.001）。
这些发现不支持精索静脉曲张会随着时间推移对生育产生渐进性不良影响这一结论，并表明需要进一步研究以确定精液参数正常的患者是否需要进行精索静脉曲张修复。
