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高危老年患者的经皮球囊主动脉瓣成形术

Percutaneous balloon aortic valvuloplasty in high-risk elderly patients.

作者信息

Park R, Schmidt D H, Shalev Y, Bajwa T K

机构信息

University of Wisconsin-Medical School, Milwaukee, USA.

出版信息

Wis Med J. 1995 Oct;94(10):537-41.

PMID:8560906
Abstract

From 1987 to mid-1994 we performed 16 percutaneous balloon aortic valvuloplasties. All patients (mean age 80 years; 53% female, 47% male) had significant congestive heart failure from aortic valve stenosis; the majority were categorized as New York Heart Association Class IV (shortness of breath at rest). Twelve patients were not surgical candidates; four patients refused surgery. After valvuloplasty, all patients became asymptomatic (NYHA Class I & II), the average preprocedure valvular gradient of 59 mm Hg decreased to 31 mm Hg, and valve area increased from 0.8 cm2 (0.3 cm2-0.98 cm2) to 1.3 cm2 (0.6 cm2-1.44 cm2). The only complications were two minor groin hematomas (2 patients). Within 6 months, 50% of the patients were symptomatic again; the overall survival rate was 23 months. We conclude that in the proper environment this procedure can be effective and safe--even in high-risk elderly patients. Although symptom improvement is transient, valvuloplasty provides a valuable opportunity to treat intercurrent medical conditions and possibly follow up with surgery.

摘要

从1987年至1994年年中,我们实施了16例经皮气囊主动脉瓣成形术。所有患者(平均年龄80岁;女性占53%,男性占47%)均因主动脉瓣狭窄而患有严重的充血性心力衰竭;大多数患者被归类为纽约心脏协会IV级(静息时呼吸急促)。12例患者不适合接受手术;4例患者拒绝手术。瓣膜成形术后,所有患者均无症状(纽约心脏协会I级和II级),术前平均瓣膜压差从59 mmHg降至31 mmHg,瓣膜面积从0.8 cm²(0.3 cm² - 0.98 cm²)增加到1.3 cm²(0.6 cm² - 1.44 cm²)。仅有的并发症是两例轻微的腹股沟血肿(2名患者)。6个月内,50%的患者再次出现症状;总体生存率为23个月。我们得出结论,在适当的环境下,即使对于高危老年患者,该手术也可以是有效且安全的。尽管症状改善是短暂的,但瓣膜成形术为治疗并发的内科疾病以及可能的后续手术随访提供了宝贵的机会。

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