Simoncelli C, Ricci G, Molini E, Pelliccioli G
Istituto di Clinica Otorinolaringoiatrica, Università di Perugia.
Acta Otorhinolaryngol Ital. 1995 Jun;15(3):229-32.
The Authors report a case history of rhinocerebral mucormycosis in a patient with chronic lymphatic leukaemia and recommend that therapy be based on three different approaches: treatment for the underlying disease, systematic antifungal treatment with Amphotericine B, and surgical asportation of diseased tissue. They affirm that results may be surprisingly successful, even in cases with signs of orbital-cerebral involvement which are indicative of a poor prognosis and the concomitant presence of a serous disease such as leukaemia.
作者报告了一例慢性淋巴细胞白血病患者发生鼻脑毛霉病的病史,并建议治疗应基于三种不同方法:治疗基础疾病、用两性霉素B进行系统性抗真菌治疗以及手术切除病变组织。他们肯定地说,即使在有眼眶-脑受累迹象(提示预后不良)且同时患有如白血病这种严重疾病的病例中,治疗结果也可能出奇地成功。