Tiefenbrunner W
Z Naturforsch C J Biosci. 1995 Nov-Dec;50(11-12):883-94.
There is no doubt that evolution can only operate in accordance with the laws of thermodynamics. To transform this simple perception into a statement that can be quantified it is necessary to examine how the entropy (or the information content) changes by means of the two main factors of evolution: selection and mutation. In the present paper this aim was reached by using the methods of information theory. That evolution becomes possible the change of information by mutation and selection must not be negative in the long run. Consequently an upper limit for the information content of the genome must be assumed. If the evolution as a self-optimizing process gains this upper limit it reaches a dynamic equilibrium at which the increase of entropy by mutation balances the decrease of entropy by selection. In particular it was examined under which circumstances of dynamic equilibrium master-genotypes (genotypes that can preserve their specific sequence over a long time) can exist.
毫无疑问，进化只能按照热力学定律进行。为了将这个简单的认识转化为一个可以量化的陈述，有必要研究熵（或信息含量）是如何通过进化的两个主要因素——选择和突变而发生变化的。在本文中，这一目标是通过使用信息论方法实现的。从长远来看，进化要成为可能，通过突变和选择引起的信息变化绝不能为负。因此，必须假定基因组信息含量的上限。如果进化作为一个自我优化的过程达到了这个上限，它就会达到一个动态平衡，在这个平衡中，突变引起的熵增加与选择引起的熵减少相平衡。特别要研究的是，在哪些动态平衡的情况下，主基因型（能够长时间保持其特定序列的基因型）能够存在。
