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1955 - 1992年挪威睾丸癌发病率趋势

Trends in incidence of testicular cancer in Norway 1955-1992.

作者信息

Wanderås E H, Tretli S, Fosså S D

机构信息

Cancer Registry of Norway, Institute for Epidemiological Cancer Research, Montebello, Oslo, Norway.

出版信息

Eur J Cancer. 1995 Nov;31A(12):2044-8. doi: 10.1016/0959-8049(95)00321-5.

Abstract

The aim of this study was to explore the incidence of testicular cancer (TC) in Norway, and thereby to increase the understanding of aetiological factors. From 1995 to 1992, a total number of 3927 TC cases were recorded in Norway, of which 51% were seminomas, 45% non-seminomas and 4% other and unspecified types. The age-standardised incidence rate increased from 2.7 to 8.5 per 100,000. The age-specific incidence rate increased in all age groups, but was most marked in the younger population. The significance of birth cohort as a risk factor for development of TC was confirmed. The incidence by birth cohorts from 1916 to 1970 showed an increase by later birth cohorts during the whole period, with the exception of a marked fall for the cohort born during the Second World War. The largest increase occurred after the war. We conclude that environmental factors acting very early in life are of significance in the development of TC.

摘要

本研究的目的是探究挪威睾丸癌(TC)的发病率,从而增进对病因学因素的理解。1995年至1992年期间,挪威共记录了3927例睾丸癌病例,其中51%为精原细胞瘤,45%为非精原细胞瘤,4%为其他及未明确分类的类型。年龄标准化发病率从每10万人2.7例增至8.5例。各年龄组的年龄别发病率均有所上升,但在较年轻人群中最为显著。出生队列作为睾丸癌发病风险因素的重要性得到了证实。1916年至1970年出生队列的发病率显示,在整个时期内,后出生队列的发病率呈上升趋势,但第二次世界大战期间出生的队列发病率明显下降。最大的增长发生在战后。我们得出结论,生命早期起作用的环境因素在睾丸癌的发生发展中具有重要意义。

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