Ordiales Fernández J J, Fernández Moya A, Nistal de Paz F, Linares Rodríguez A, Colubi Colubi L, Alvarez Asensio E, Rodrigo Sáez L
Sección de Neumología, Complejo Hospitalario de León.
Rev Esp Enferm Dig. 1995 Dec;87(12):853-7.
The thoracic cavity plays an important role in the mechanical ventilatory function, and the alteration of some of its structures, such as those which occur in decompensated cirrhosis of the liver, for example the presence of ascites and muscle atrophy, directly influence its normal function.
In the present study we have evaluated the ventilatory function and respiratory muscular tension by means of the calculation of volumes, flows and resistances of the airways, and also the maximum inspiratory and expiratory pressures (Pimax, Pemax).
One hundred patients with liver cirrhosis and ascites without associated respiratory illness, mean age 57 +/- 15 years (range 32-80), were studied. We evaluated the respiratory function before and after the disappearance of the ascites.
A restrictive pattern was evident, and various parameters were altered. The most affected being that of the reserve expiratory volume. No associated bronchial obstruction was observed. Respiratory muscular tension was decreased in both the Pimax and the Pemax. With the disappearance of the ascites we found an improvement in the affected parameters, but this did not reach normality.
In liver cirrhosis associated with ascites, the most common respiratory pattern, is a decrease in ventilatory function of a restrictive type, and also a decrease in the respiratory muscular tension. These alterations improve after the resolution of the ascites.
胸腔在机械通气功能中起重要作用,其某些结构的改变,如在失代偿期肝硬化中出现的结构改变,例如腹水的存在和肌肉萎缩,直接影响其正常功能。
在本研究中,我们通过计算气道的容积、流量和阻力,以及最大吸气和呼气压力(Pimax、Pemax)来评估通气功能和呼吸肌张力。
研究了100例无相关呼吸系统疾病的肝硬化腹水患者,平均年龄57±15岁(范围32 - 80岁)。我们在腹水消失前后评估了呼吸功能。
明显呈现限制性模式,且多个参数发生改变。受影响最大的是呼气储备量参数。未观察到相关支气管阻塞。Pimax和Pemax的呼吸肌张力均降低。随着腹水的消失,我们发现受影响的参数有所改善,但未恢复正常。
在伴有腹水的肝硬化中,最常见的呼吸模式是限制性通气功能降低,以及呼吸肌张力降低。腹水消退后这些改变会有所改善。