Kodama M, Kodama T
Kodama Research Institute of Preventive Medicine, Nagoya, Japan.
In Vivo. 1995 May-Jun;9(3):231-8.
The purpose of this review paper is to present relevant information for assessing the validity of our clinical investigation on the clinical usefulness of vitamin C infusion treatment tested in the control of autoimmune disease and allergy. Firstly, we describe the historical background of this study and then present the results of both experimental and clinical investigations as regards the therapeutic effect of vitamin C infusion treatment for the control of immune disorders including diabetes mellitus. Secondly, we discuss the interdisciplinary nature of our studies in the light of recent progress in clinical vitaminology, endocrinology and immunology. Thirdly, we suggest the possibility that the use of our vitamin C infusion treatment may be beneficial in the clinical management of AIDS, of which the immunological background data are in favor of the participation of an autoimmune mechanism in the genesis of this disease. Finally, we stress the importance of paradigm change in the achievement of a breakthrough in natural science.
这篇综述论文的目的是提供相关信息，以评估我们关于维生素C输注治疗在自身免疫性疾病和过敏控制中临床效用的临床研究的有效性。首先，我们描述本研究的历史背景，然后呈现关于维生素C输注治疗对包括糖尿病在内的免疫紊乱控制的治疗效果的实验和临床研究结果。其次，我们根据临床维生素学、内分泌学和免疫学的最新进展，讨论我们研究的跨学科性质。第三，我们提出使用我们的维生素C输注治疗可能对艾滋病临床管理有益的可能性，艾滋病的免疫背景数据支持自身免疫机制参与该疾病的发生。最后，我们强调范式转变在自然科学取得突破中的重要性。
