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[恶性眼睑肿瘤的冷冻疗法]

[Cryotherapy of malignant eyelid tumors].

作者信息

Anders M, Spörl E, Krantz H, Matthäus W, Seiler T

机构信息

Augenklinik Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden.

出版信息

Ophthalmologe. 1995 Dec;92(6):787-92.

PMID:8563426
Abstract

The treatment of tumors of the eyelids must extend not only to complete removal or destruction of the neoplasm, but also to the maintenance of physiology functions. In addition, cosmetic aspects should be taken into consideration. In a prospective study, 278 cryosurgical operations performed for lid tumors in the years from 1980 to 1985 were followed up for 5 years to decide whether cryotherapy fulfilled these demands. We used spray freezing with liquid nitrogen, because the low temperatures and high freezing rates required for cell destruction are achieved only by this technique. The 5-year recurrence rate was 3.5%. The liquid nitrogen therapy is especially suitable when the eye lids are operated on, because the lacrimal system remains functional. Gas expansion cryotherapy should not be used in in the treatment of tumors, as it may lead to stimulation of growth.

摘要

眼睑肿瘤的治疗不仅要彻底切除或破坏肿瘤,还要维持生理功能。此外,还应考虑美容方面。在一项前瞻性研究中,对1980年至1985年期间为眼睑肿瘤进行的278例冷冻手术进行了5年的随访,以确定冷冻疗法是否满足这些要求。我们使用液氮喷雾冷冻,因为只有这种技术才能达到细胞破坏所需的低温和高冷冻速率。5年复发率为3.5%。液氮疗法特别适用于眼睑手术,因为泪腺系统仍能保持功能。气体膨胀冷冻疗法不应应用于肿瘤治疗,因为它可能导致肿瘤生长。

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