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多发性肌炎

Polymyositis.

作者信息

Bradley W G

出版信息

Br J Hosp Med. 1977 Apr;17(4):351, 353-5.

PMID:856365
Abstract

Polymyositis is a treatable and curable disease. Unfortunately, patients with polymyositis are still frequently diagnosed as having muscular dystrophy. It is important to have a high index of suspicion of polymyositis, and to recognize that the detailed symptoms and signs and the overall picture are different from the relatively clear-cut pattern of the muscular dystrophies. Treatment of polymyositis is rewarding, although it frequently requires considerable resilience from both patient and doctor to achieve the best results. A detailed search for an underlying aetiology should be made, and a carcinoma should be suspected in elderly patients and those with dermatomyositis. In patients in whom polymyositis is related to a carcinoma, the latter may be at a stage where total excision is possible.

摘要

多发性肌炎是一种可治疗且可治愈的疾病。不幸的是,多发性肌炎患者仍常被误诊为患有肌肉萎缩症。高度怀疑多发性肌炎并认识到其详细的症状、体征及整体表现与相对明确的肌肉萎缩症模式不同很重要。治疗多发性肌炎是有成效的,尽管通常需要患者和医生都具备相当的适应能力才能取得最佳效果。应详细查找潜在病因,对于老年患者及皮肌炎患者应怀疑有癌症。在多发性肌炎与癌症相关的患者中,后者可能处于可完全切除的阶段。

相似文献

1
Polymyositis.多发性肌炎
Br J Hosp Med. 1977 Apr;17(4):351, 353-5.
2
[Myositis in the presence of slightly elevated creatine kinase values].肌酸激酶值轻度升高情况下的肌炎
Ned Tijdschr Geneeskd. 1999 May 1;143(18):949-53.
3
Inclusion body myositis: clinical and pathological boundaries.包涵体肌炎:临床与病理界限
Ann Neurol. 1996 Oct;40(4):581-6. doi: 10.1002/ana.410400407.
4
[135 cases of polymyositis].
Rev Neurol (Paris). 1986;142(12):906-17.
5
Dermatomyositis and polymyositis: clinical aspects.皮肌炎和多发性肌炎:临床方面
Clin Exp Rheumatol. 1984 Jul-Sep;2(3):271-7.
6
[Acute renal failure after massive myolysis in pseudomyopathic polymyositis (author's transl)].
Dtsch Med Wochenschr. 1974 May 17;99(20):1084-7. doi: 10.1055/s-0028-1107895.
7
[Therapeutic strategies in idiopatic inflammatory myopathies].[特发性炎性肌病的治疗策略]
Rev Med Suisse. 2009 Apr 15;5(199):812-8.
8
Prognosis in adult polymyositis.成人多发性肌炎的预后
J Neurol Sci. 1975 Sep;26(1):71-80. doi: 10.1016/0022-510x(75)90115-x.
9
Influence of age at onset on the duration of treatment in idiopathic adult polymyositis and dermatomyositis.发病年龄对特发性成人多发性肌炎和皮肌炎治疗持续时间的影响。
Arch Intern Med. 1987 Nov;147(11):1989-91.
10
Diagnosis and treatment of polymyositis and dermatomyositis.多发性肌炎和皮肌炎的诊断与治疗
Compr Ther. 1990 Apr;16(4):16-24.

引用本文的文献

1
Effects of intravenous immunoglobulin therapy in Japanese patients with polymyositis and dermatomyositis resistant to corticosteroids: a randomized double-blind placebo-controlled trial.静脉注射免疫球蛋白治疗对皮质类固醇耐药的日本皮肌炎和多发性肌炎患者的疗效:一项随机双盲安慰剂对照试验。
Mod Rheumatol. 2012 Jun;22(3):382-93. doi: 10.1007/s10165-011-0534-4. Epub 2011 Oct 5.
2
Antibodies to nuclear antigens in polymyositis: relationship to autoimmune 'overlap syndromes' and carcinoma.多发性肌炎中核抗原抗体:与自身免疫性“重叠综合征”及癌症的关系。
Ann Rheum Dis. 1981 Jun;40(3):217-23. doi: 10.1136/ard.40.3.217.