接触三硝基甲苯的工人精液中某些元素浓度的改变。
Some altered concentrations of elements in semen of workers exposed to trinitrotoluene.
作者信息
Liu H X, Qin W H, Wang G R, Yang Z Z, Chang Y X, Jiang Q G
机构信息
He-Nan Institute of Occupational Disease, Zheng-Zhou, China.
出版信息
Occup Environ Med. 1995 Dec;52(12):842-5. doi: 10.1136/oem.52.12.842.
OBJECTIVES
A cross sectional study was performed to find the concentrations of elements contained in the semen of workers exposed to trinitrotoluene (TNT).
SUBJECTS AND METHODS
Semen of exposed workers in two TNT plants located in He-Nan Province in 1992 were examined.
RESULTS
The average TNT concentrations in the workplace, except the packing site, were found to have exceeded the maximal allowable concentration (MAC, 1 mg/m3); skin contaminations of male workers exposed to TNT were higher after a shift than in controls, and correlated with the total blood concentrations of TNT, 4-amino-2, 6-dinitrotoluene (4A), and 2-amino-4, 6-dinitrotoluene (2A). Cu, Zn, Na, Mg, and Se concentrations were significantly decreased, but K, Ca, Co, Mn and Li contents were not significantly changed in the semen of workers exposed to TNT. Compared with the control group, the percentage of liquifying time of semen, the sperm malformation incidence, and viability in the men exposed to TNT were all significantly changed.
CONCLUSIONS
Men exposed to TNT have decreased concentrations of some elements is semen and altered semen physiology.
目的
开展一项横断面研究，以测定接触三硝基甲苯（TNT）的工人精液中的元素浓度。
对象与方法
对1992年河南省两家TNT工厂中接触TNT的工人的精液进行检测。
结果
发现除包装车间外，工作场所的TNT平均浓度超过了最大允许浓度（MAC，1毫克/立方米）；接触TNT的男性工人下班后皮肤污染程度高于对照组，且与TNT、4-氨基-2,6-二硝基甲苯（4A）和2-氨基-4,6-二硝基甲苯（2A）的全血浓度相关。接触TNT的工人精液中铜、锌、钠、镁和硒的浓度显著降低，但钾、钙、钴、锰和锂的含量无显著变化。与对照组相比，接触TNT的男性精液液化时间百分比、精子畸形发生率和活力均有显著改变。
结论
接触TNT的男性精液中某些元素浓度降低，精液生理发生改变。
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