Stonebridge P A, Draper T, Kelman J, Howlett J, Allan P L, Prescott R, Ruckley C V
University Department of Surgery, Royal Infirmary, Edinburgh University, U.K.
Eur J Vasc Endovasc Surg. 1996 Jan;11(1):70-3. doi: 10.1016/s1078-5884(96)80137-7.
To delineate the natural history of infrarenal aortic aneurysms with respect to growth rate.
A referral based series of 233 patients with abdominal aortic aneurysm was serially assessed by abdominal ultrasound.
The mean age was 71 years and the median follow up 26 months (range 6-146). The mean growth rate of the series was 3.2mm/year. Division of the initial size into those less than 41 mm (128 patients), between 41-60 mm (92 patients) and those above 60 mm (13 patients) in AP diameter showed mean growth rates per year were 2.6 mm/year, 4.1 mm/year and 6.5 mm/year. Examination of the relationship between aneurysm size and subsequent growth rate over the whole study period revealed a rank correlation of 0.19 (p = 0.002). Aneurysms were also observed to expand at an erratic rate both in terms of time and size.
When the initial decision is to observe the patient, serial ultrasound examinations facilitate later judgements on the balance of risks in relation to surgical treatment.
描述肾下腹主动脉瘤的自然生长史及其生长速率。
通过腹部超声对233例腹主动脉瘤患者进行系列评估。
患者平均年龄71岁，中位随访时间26个月（范围6 - 146个月）。该系列患者的平均生长速率为每年3.2毫米。根据腹主动脉前后径初始大小将患者分为小于41毫米（128例）、41 - 60毫米（92例）和大于60毫米（13例）三组，其每年平均生长速率分别为2.6毫米/年、4.1毫米/年和6.5毫米/年。在整个研究期间，对动脉瘤大小与后续生长速率之间的关系进行检查，发现秩相关系数为0.19（p = 0.002）。还观察到动脉瘤在时间和大小方面的扩张速率不稳定。
当最初决定对患者进行观察时，系列超声检查有助于后期判断手术治疗的风险平衡。
