一种用于测定人血清或血浆中苯丙香豆素（3-(1-苯基丙基)-4-羟基香豆素，Marcoumar，Liquamar）的气相色谱法。
A gas chromatographic method for the estimation of phenprocoumon, 3-(1-phenyl-propyl)-4-hydroxycoumarin (Marcoumar, Liquamar), in human serum or plasma.
作者信息
Brombacher P J, Cremers H M, Mol M J, Muijrers P H, Van der Plas P M, Verheesen P E
出版信息
Clin Chim Acta. 1977 Mar 15;75(3):443-8. doi: 10.1016/0009-8981(77)90364-3.
PMID:856495
Abstract
A rapid and reliable gas-chromatographic method is described for the estimation of phenprocoumon from human serum or plasma. No interference was found from other usual oral anticoagulant drugs. The method can be used for therapeutic and toxic levels. The appearance of two volatile derivatives of phenprocoumon (in constant ratio) is discussed.
摘要
本文描述了一种快速可靠的气相色谱法，用于测定人血清或血浆中的苯丙香豆素。未发现其他常用口服抗凝药物的干扰。该方法可用于治疗水平和中毒水平的检测。文中还讨论了苯丙香豆素两种挥发性衍生物（比例恒定）的出现情况。
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