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用高效液相色谱法(HPLC)测定3-(1'-苯丙基)-4-羟基香豆素(作者译)

[Determination of 3-(1'-phenylpropyl)-4-hydroxycoumarin by means of high-performance liquid chromatography (HPLC) (author's transl)].

作者信息

Kinawi A

出版信息

Arzneimittelforschung. 1977 Feb;27(2):360-3.

PMID:577154
Abstract

Marcumar [3-(1-phenylpropyl)-4-hydroxycoumarin] was determined by means of high-performance liquid chromatography from serum extracts after the oral application of its sodium salt solution. 4-Hydroxycoumarin was used as the internal standard and rats were used as the test animals. Furthermore mixtures containing anticoagulants and anti-epileptics were also analysed with the help of high-performance liquid chromatography.

摘要

在口服其钠盐溶液后,通过高效液相色谱法从血清提取物中测定了华法林(3 - (1 - 苯基丙基)-4 - 羟基香豆素)。以4 - 羟基香豆素作为内标,使用大鼠作为实验动物。此外,还借助高效液相色谱法分析了含有抗凝剂和抗癫痫药的混合物。

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