Suppr超能文献

一例横纹肌溶解症合并心肌损伤

[A case of rhabdomyolysis complicated with myocardial injury].

作者信息

Aizawa H, Morita K, Minami H, Sasaki N, Tobise K, Yahara O

机构信息

Department of Internal Medicine, National Hospital Nayoro.

出版信息

Rinsho Shinkeigaku. 1995 Sep;35(9):1051-3.

PMID:8565347
Abstract

A 22-year-old man developed transient unconsciousness during running. He developed fever, nausea, vomiting, diarrhea and general fatigue. Next day, he was admitted to National Hospital Nayoro because of high serum CK level of 13,610U/l. Biochemical analyses revealed elevated serum myoglobin, increased CK-MM isozyme, aldolase and lactate dehydrogenase, increased serum osmolality, increased uric acid, and decreased serum potassium levels. Therefore, he was diagnosed as having rhabdomyolysis. In addition, serum CK-MB isozyme, cardiac myosin light chain I and troponin T were increased, suggesting the damage of cardiac muscle. Electrocardiogram showed elevated ST segment and inverted T on V2-4, which were not observed previously. He had no preceding infectious disease, drug ingestion or an underlying metabolic disorder. The rhabdomyolysis may be precipitated by the superimposition of dehydration and loss of potassium due to diarrhea and vomiting. The myocardial injury, probably produced by transient myocardial ischemia, should be paid attention in case of rhabdomyolysis.

摘要

一名22岁男性在跑步过程中出现短暂意识丧失。他还出现发热、恶心、呕吐、腹泻及全身乏力症状。次日,因其血清肌酸激酶(CK)水平高达13610U/l而入住钏路国立医院。生化分析显示血清肌红蛋白升高、CK-MM同工酶、醛缩酶及乳酸脱氢酶增加,血清渗透压升高,尿酸增加,血清钾水平降低。因此,他被诊断为横纹肌溶解症。此外,血清CK-MB同工酶、心肌肌球蛋白轻链I及肌钙蛋白T升高,提示心肌受损。心电图显示V2 - 4导联ST段抬高及T波倒置,此前未见此表现。他既往无传染病、药物摄入史或潜在代谢紊乱。腹泻和呕吐导致的脱水及钾丢失叠加可能促使横纹肌溶解症发生。横纹肌溶解症患者应注意可能由短暂心肌缺血引起的心肌损伤。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验