Apiou F, Rumpler Y, Warter S, Vezuli A, Dutrillaux B
UMR 147 CNRS--Institut Curie, Paris, France.
Cytogenet Cell Genet. 1996;72(1):50-2. doi: 10.1159/000134160.
Human-specific probes for chromosomes 3, 7, 9, 14, 19, and 21 were used to paint chromosomes of three lemur species: Eulemur fulvus mayottensis, E. macaco macaco, and Lemur catta. Chromosomes 1 and 3 of E. f. mayottensis are homoeologous to human chromosomes 3, 9, 14, and 21, as previously suggested by chromosome banding. Probes for human chromosomes 7 and 19 produced unexpectedly strong signals in the centromeric regions of all lemur chromosomes, suggesting that sequences homologous to nonrepeated sequences of the human genome have been amplified during the formation of constitutive heterochromatin in lemurs.
使用针对人类3号、7号、9号、14号、19号和21号染色体的特异性探针来标记三种狐猴物种的染色体：马约特褐狐猴（Eulemur fulvus mayottensis）、黑冠猕猴（E. macaco macaco）和环尾狐猴（Lemur catta）。如先前染色体带型分析所表明的，马约特褐狐猴的1号和3号染色体与人类3号、9号、14号和21号染色体是同源的。人类7号和19号染色体的探针在所有狐猴染色体的着丝粒区域产生了意外强烈的信号，这表明与人类基因组非重复序列同源的序列在狐猴组成型异染色质形成过程中发生了扩增。
